Unveiled during the recent 2011 Medical Innovation Summit, the Cleveland Clinic announced the Top 10 Medical Innovations for 2012. The list of breakthrough devices and therapies was selected by a panel of Cleveland Clinic physicians and scientists.

Nominated innovations were required to: Have significant potential for short-term clinical impact; Have a high probability of success; Be on the market or close to being introduced; Have sufficient data available to support its nomination.

Among them are:

Genetically modified mosquitoes to reduce disease threat.

Novel diabetes therapy that represents a paradigm shift in diabetes treatment.

Harnessing big data to improve heath care.

Active bionic prosthesis with microprocessors and computer chips that can rival the functionality provided by biological limbs.

Implantable devices to treat complex brain aneurysms.

Next-generation gene sequencing to get to the root cause of serious illness.

Medical apps for mobile devices.

Concussion management system for athletes that provide patient-specific guidance about when athletes can return to play without risk of further harm.

CT Scans for early detection of lung cancer.

Read the full report here.