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rawlings and cleveland clinic team up for sports research
The Associated Press outlines a new collaboration between the Cleveland Clinic and helmet-maker Rawlings to conduct research on concussions and other sports-related head and neck injuries that could include measuring the impact on the brain.

Doctors and scientists from the clinic's Neurological Institute and its Spine Research Laboratory will use equipment manufactured and donated by Rawlings to do research on helmets and other protective accessories used in both baseball and football. They will measure the equipment's ability to minimize impacts and will seek ways to assess the amount of injury to the brain, both initially and over time.

The Cleveland Clinic research team is led by Spine Research Laboratory director Lars Gilbertson, who says "concussion has become a signature injury of sports in this new millennium." The studies will try to determine the effects of single and multiple impacts to the heads of athletes and how to reduce those injuries through protective equipment.

Read the entire article here.
new cleveland brand of drink mixes proves blondes have more fun, especially when they're hungarian
The spice of life might just be found inside a Budapest Blonde Cocktail Mix. Created by Clevelander Ilona Simon, the new drink mixes promise to offer loads of taste but few calories.

The Hot Blonde Bloody Mary mix features fresh tomato puree, Hungarian paprika, mustard powder and wasabi - for that special kick. The best part: The tasty mix has only 10 calories per serving, according to Simon, although adding vodka will increase the calorie content (and, ahem, the fun).

Budapest Blonde also offers a Dirty Blonde olive martini mix (40 calories per serving), and the Beach Blonde margarita and mojito mix (also 40 calories per serving).

Simon, who was co-owner of the former Budapest Blonde Wine & Martine Bar in Independence, says that her new mixes provide great flavor without any artificial or unhealthy ingredients. "They don't have all those preservatives; they don't have all that sodium; and they don't have all those calories," she says. Teetotalers needn't feel left out. "[The mixes] are so good, you can even drink them straight from the bottle," Simon declares.

These days, you'll find Simon's Budapest Blonde Cocktail Mixes at Heinen's in Brecksville, Independence Beverage, Minotti's Wine & Spirits and Shoregate Beverage, among other locations. For more information, visit the Budapest Blonde Facebook page: Budapest Blonde Cocktail Mix


SOURCE: Ilona Simon
WRITER: Diane DiPiero
stem-cell therapy from athersys shows promise in brain injuries and heart attacks
The October issue of the journal Experimental Neurology reports on a study showing that MultiStem, a patented adult stem cell therapy product from Cleveland-based biopharmaceutical firm Athersys Inc., mitigated the damage of traumatic brain injuries in lab experiments.

MultiStem uses multipotent adult progenitor cells, or MAPC, which "are obtained from the bone marrow or other tissue sources of healthy, consenting adult donors," according to an Athersys release. In an abstract of the study, the researchers explain, "Traumatic brain injury causes … an increase in circulating immune cells leading to increased blood brain barrier permeability. The intravenous injection of MAPC preserves … the integrity of the blood brain barrier."

As an unrelated 2007 Science Daily article explained, "The cells that make up the blood-brain barrier help the brain and immune system communicate. … Changes to the blood-brain barrier could give important clues about injuries to the central nervous system and the growth of tumors."

MultiStem appears to be an unusually versatile therapy. The same week that the Experimental Neurology report was released,
Athersys presented findings from clinical trials with heart attack patients at Transvascular Cardiovascular Therapeutics Conference in Washington, D.C. That ongoing work involves Dr. Marc Penn, Director of Cardiovascular Cell Therapy at the Cleveland Clinic. Athersys CEO Gil Van Bokkelen notes that while the recent trials were designed primarily to test safety, "we also saw clear and compelling signs that patients were experiencing improvement in heart function."

Van Bokkelen says Athersys and its many partners, including Pfizer, are excited about the potential of MultiStem as a "very powerful multifactor delivery system" that can treat a wide variety of patients.




Source: Athersys
Writer: Frank W. Lewis
after years of waiting, the syrian cultural garden begins to bloom
For decades it was merely a dream, but soon, the Syrian Cultural Garden becomes a reality. Part of the Cleveland Cultural Gardens that wend along Rockefeller Park, the Syrian Garden is in progress on Martin Luther King Boulevard across from the Indian Garden. Upon completion, it will be the first of the Cultural Gardens representing an Arab country.

About 80 years ago, Cleveland's Syrian community received a garden site on which to commemorate its culture and heritage. Plagued by lack of funding followed by waning interest, the plot of land sat undeveloped for many years. But around 2007, the notion of a Syrian Cultural Garden began to once again take shape, with members of Cleveland's Syrian community becoming involved in design and fundraising efforts.

Sponsored by the Syrian Cultural Gardens Association, in collaboration with the Syrian American Cultural Council, the garden will have at its focus a series of classically inspired arches designed by University of Damascus architecture students Raghda Helal and Nagham Nano. The Arches of Palmyra, the Amphitheater of Basra, the Syrian Arch and the Arabic Fountain all served as inspiration. The history of Syria will be displayed on several granite stones along the amphitheater, according to Layla George-Khouri, one of the founders of the garden committee. Damascene roses will surround the architectural feature.

"It's going to be beautiful," says Khouri, adding that the goal is to unveil the finished garden to the public in April of 2011.

The Cleveland Cultural Gardens date back to 1926, when the Shakespeare Garden (which later became known as the British Garden) was dedicated to honor the Bard. Through the years, many other ethnic groups have planted flowers and built monuments as a tribute to the land of their ancestors. Check out this link for detailed information about all of the gardens, as well as a map.


SOURCE: Layla George-Khouri
WRITER: Diane DiPiero
travel + leisure loves lakewood... and long walks on the beach
Sip on this, Lakewood. Travel + Leisure tapped your fair city as one of the "Coolest Suburbs Worth a Visit." Nice company, too, as share space with tony Montclair, NJ, beachy La Jolla, CA, and thirst-quenching Golden, CO.
cervilenz inc. offers another tool for doctors and pregnant women
Five months after the commercial launch of its medical device, CerviLenz Inc. of Chagrin Falls is ramping up for a national marketing push in the third quarter.

The wand-like CerviLenz measures the vaginal cervical length of pregnant women showing signs of preterm labor. In August, Ob.Gyn. News reported that in a study involving 52 women, CerviLenz was "similar in efficacy" to another widely used test that, unlike a CerviLenz test, requires lab work.

"Immediate and quantifiable measures of cervical length using the CerviLenz probe may be less variable than the most common way of measuring — by digital exam — and speedier than waiting for fetal fibronectin [test] results," according to Ob.Gyn. News.

The device helps reduce the guesswork in treatment: The article notes that only 21-27 percent of women with symptoms of preterm labor will actually deliver prematurely. And, "In asymptomatic women, cervical length shorter than 25 mm has been linked to a sixfold increase in risk for preterm birth."

About 25 hospitals are currently evaluating the product. "The hospital purchasing process is really complicated," with multiple rounds of testing, says Melanie Sweeney, CerviLenz Inc.'s director of marketing. But the company should soon start receiving the feedback it will need for a major sales push.

CerviLenz Inc.'s backers include Cleveland-based JumpStart Inc., North Coast Angel Fund of Mayfield Heights and Chrysalis Ventures, which has a Cleveland office.



Source: CerviLenz Inc.
Writer: Frank W. Lewis
contemporary art museum to get contemporary new home
It has always been a bit of an oxymoron: The Museum of Contemporary Art, Cleveland (MOCA) housed in a building with as much contemporary flair as an old-fashioned Cracker Jack box. And while visitors still came to the Carnegie Avenue location to admire the museum's growing collection of contemporary art, many surely wondered why such a gem wasn't located in University Circle with other great museums, especially the Cleveland Museum of Art.

Turns out, MOCA was wondering the same thing. The museum had been planning for ten years to leave its Carnegie Avenue location for a permanent home that reflected the cutting-edge and forward-thinking image for which MOCA has been known. That vision will soon take shape at the corner of Euclid and Mayfield in University Circle.

The new museum building will be part of a long-planned project that will bring restaurants, stores and housing to that section of Euclid Avenue.

In addition to a comfortable place to exhibit and store the museum's collections, the new MOCA building will help the museum increase its educational and public programs.

Farshid Moussavi with Foreign Office Architects of London designed the building, which will rely on clean lines and sharp angles made from glass and black steel to create a structure that promises to be as intriguing as the art displayed inside. According to the MOCA website, "The lobby is designed as an urban living room, a place for visitors to mingle, eat, shop, attend events, over the course of hours, or for brief interludes in a busy day. The building itself is a learning environment, infused at each level with education offerings that range from low tech to high tech, from contemplative to interactive, from solitary to group encounters. This building is an opportunity to provide a 21st century model of an art museum that anticipates dramatic shifts in how we learn, how we see, and how we socialize."

Jill Snyder, director of MOCA, is pleased with the multipurpose design an aesthetic appeal of the new building. "FOA's design for our building is the perfect expression of our program--one that will not only enable us to operate at the highest level, but that will also be beautiful, intriguing and sensitive to our urban surroundings and community."

The Cuyahoga County Planning Commission reports that MOCA hopes to break ground on the new museum building in late fall. The project is estimated at $26 million.


SOURCE: Jill Snyder
WRITER: Diane DiPiero